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nucleotide_freqs_by_site – Based on a directory of aligned FASTA files, generates a directory of tables providing the number of occurances of each base at each position in the alignment and a single table summarising the.

Single-nucleotide methylation specifically represses type I interferon in antiviral innate immunity – We performed whole-genome bisulfite sequencing and found that a single-nucleotide methylation site in the Ifnb promoter region disrupted IRF3 recruitment. We used site-specific mutant knock-in mice.

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The estimate supplied with the aid of Fraser et al. Is based totally on a genomewide frequency of SNPs (1/three,000 nucleotide web sites), 50% of which possibly are placed in intergenic regions and 50% in structural genes.